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KMID : 0378119920190020455
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Chungnam Medical Journal
1992 Volume.19 No. 2 p.455 ~ p.462
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The Effects of Propofol(DiprivanR) and Thiopentone on intraocular Pressure
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Abstract
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The effects of Propofol and thiopentone on intraocular pressure and cardiovascular system was evaluated during induction of anesthesia in twenty patients.
All patients were devided into two group as follows :
Group I(n=10): thiopentone 5mg/kg was administered intravenously for induction of anesthesia.
Group II(n=10) : propofol 2mg/kg was administered intravenously for induction of anesthesia
The changes of systolic and diastolic blood pressure, heart rate and intracocular pressure was measured before induction, after induction and at 1 min. and 3 min. after intubation in all groups. Succinlycholine 1-1.5mg/kg was administered
intravenously
for endotracheal intubation.
@ES The results were as follows :
@EN 1. There were no significant difference in the effects of propofol and thiopentone on cardiovascular system and intraocular pressure.
2. There were significant increase in systolic and diastolic blood pressure, and heart rate after intubation in both groups, but lesser degree of increase in propofol group than thiopentone group.
3. Induction of anesthesia with propofol or thiopentone was associated with a significant decrease in intraocular pressure.
From the above results, propofol can be used as effectively as thiopentone for anesthesia in patients who undergo opthalmic surgery.
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